产品货号:
Z32128
中文名称:
CLOCK抗体
英文名称:
Anti-CLOCK Antibody (Clone#OTI2C3)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CLOCK Antibody (Clone#OTI2C3) |
指标别名 | bHLHe8;CLOCK;clock homolog (mouse);hCLOCK;KAT13D;KIAA0334 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | CLOCK |
克隆号 | OTI2C3 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Human recombinant protein fragment corresponding to amino acids 1-285 of human CLOCK (NP_004889) produced in E.coli. |
实际分子量 | 95.1KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | Clock (Circadian Locomotor Output Cycles Kaput) is also known as KAT13D.The protein encoded by this gene plays a central role in the regulation of circadian rhythms.This protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity.And the encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1,PER2,PER3) and Cryptochrome (CRY1,CRY2) genes and activates transcription of these genes.PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes.Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome.Alternative splicing results in multiple transcript variants. |
Uniprot ID | O15516 |
基因名全称 | clock circadian regulator |
蛋白名全称 | Circadian locomoter output cycles protein kaput |
推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索:CLOCK抗体,CLOCK单抗,Anti-CLOCK Antibody (Clone#OTI2C3)